Index / Inventions / Penicillin
Inventions
Penicillin
Fleming (1928) · the first antibiotic
A Penicillium mould contaminated a petri dish, inhibiting bacterial growth around it, and Fleming noticed. The β-lactam ring locks a transpeptidase enzyme bacteria use to build their cell walls — lysis follows. Life expectancy jumped.
Key specifications
Discovered
1928 · Fleming
Mass-produced
1940 – 41 · Florey & Chain
Nobel Prize
1945
Class
β-lactam
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